REM sleep without atonia after lesions of the medial medulla.
| Title | REM sleep without atonia after lesions of the medial medulla. |
| Publication Type | Journal Article |
| Year of Publication | 1989 |
| Authors | Schenkel E, Siegel JM |
| Journal | Neurosci Lett |
| Volume | 98 |
| Issue | 2 |
| Pagination | 159-65 |
| Date Published | 1989 Mar 27 |
| ISSN | 0304-3940 |
| Keywords | Acetylcholine, Animals, Cats, Glutamates, Glutamic Acid, Medulla Oblongata, Muscle Tonus, Sleep, REM |
| Abstract | Rapid eye movement (REM) sleep is normally accompanied by a complete suppression of tone in the antigravity musculature. Pontine lesions have been shown to block this suppression, producing a syndrome of REM sleep without atonia. We now report that glutamate-induced lesions of the medial medulla, including the nucleus magnocellularis, caudal nucleus gigantocellularis and rostral nucleus paramedianus, produce REM sleep without atonia. These nuclei may function as part of a ponto-medullary system suppressing muscle tone in REM sleep. |
| DOI | 10.1016/0304-3940(89)90503-x |
| Alternate Journal | Neurosci Lett |
| PubMed ID | 2565566 |
| Grant List | HL41370 / HL / NHLBI NIH HHS / United States MH43811 / MH / NIMH NIH HHS / United States NS14610 / NS / NINDS NIH HHS / United States |
